Walter Isaacson returns with a gripping account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have better babies. She and her collaborators turned a curiosity of nature in to an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. Children who study digital coding will be joined by those who study genetic code. After helping to discover CRISPR, Doudna became a leader in wrestling with its moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is a thrilling detective tale that involves the most profound wonders of nature, from the origins of life to the future of our species.

The author of The Professor and the Madman and The Perfectionists explores the notion of property--our proprietary relationship with the land--through human history, how it has shaped us and what it will mean for our future. Land--whether meadow or mountainside, desert or peat bog, parkland or pasture, suburb or city--is central to our existence. It quite literally underlies and underpins everything. Employing the keen intellect, insatiable curiosity, and narrative verve that are the foundations of his previous bestselling works, Simon Winchester examines what we human beings are doing--and have done--with the billions of acres that together make up the solid surface of our planet. Land: How the Hunger for Ownership Shaped the Modern World examines in depth how we acquire land, how we steward it, how and why we fight over it, and finally, how we can, and on occasion do, come to share it. Ultimately, Winchester confronts the essential question: who actually owns the world's land--and why does it matter? 

A memoir of being in the right place at the right time, and of the mysterious ways a beloved pet can bring people together, from CBS Sunday Morning News correspondent and multi-Emmy-Award-winning Martha Teichner. There's a special camaraderie among early-morning dog walkers. Fellow pet owners become familiar-as do the personalities of their beloved animals. A chance encounter with an old acquaintance changed Martha Teichner's world. As fate would have it, her friend knew someone who was dying of cancer, from exposure to toxins after 9/11,and desperate to find a home for her dog, Harry. He was a Bull Terrier--the same breed as Martha's dear Minnie. Would Martha consider giving Harry a safe, loving new home? In short order, boy dog meets girl dog, the fairy tale part of this story. After Martha agrees to meet Harry and his owner Carol, what begins as a transaction involving a dog becomes a deep and meaningful friendship between two women with complicated lives and a love of Bull Terriers in common. Through the heartbreak and grief of Carol's illness, the bond that develops changed Martha's life, Carol's life, Minnie's life, Harry's life. As it changed Carol's death as well. In this rich and touching narrative, Martha considers the ways our stories are shaped by the people we meet, and the profound love we can find by opening our hearts to unexpected encounters.

For four thousand years, the size and vitality of cities, economies, and empires were heavily determined by infection. The cycle of plagues set the tempo of civilizational growth and decline, since common response to the threat was exclusion--quarantining the sick or keeping them out. But the unprecedented hygiene and medical revolutions of the past two centuries have allowed humanity to free itself from the hold of epidemic cycles--resulting in an urbanized, globalized, and unimaginably wealthy world. However, our development has lately become precarious. Climate and population fluctuations and aspects of our prosperity such as global trade have left us more vulnerable than ever to newly emerging plagues. Greater global cooperation toward sustainable health is urgently required--such as the international efforts to harvest a Covid-19 vaccine--with millions of lives and trillions of dollars at stake. Written as colorful history, The Plague Cycle reveals the relationship between civilization, globalization, prosperity, and infectious disease over the past five millennia.

A groundbreaking and endlessly surprising history of how artisans created America, from the nation's origins to the present day. At the center of the United States' economic and social development, according to conventional wisdom, are industry and technology while craftspeople and handmade objects are relegated to a bygone past. Renowned historian Glenn Adamson turns that narrative on its head in this innovative account, revealing makers' central role in shaping America's identity. Examine any phase of the nation's struggle to define itself, and artisans are there from the silversmith Paul Revere and the revolutionary carpenters and blacksmiths who hurled tea into Boston Harbor, to today's "maker movement." From Mother Jones to Rosie the Riveter. From Betsy Ross to Rosa Parks. From suffrage banners to the AIDS Quilt. Adamson shows that craft has long been implicated in debates around equality, education, and class. Artisanship has often been a site of resistance for oppressed people, such as enslaved African-Americans whose skilled labor might confer hard-won agency under bondage, or the Native American makers who adapted traditional arts into statements of modernity. Theirs are among the array of memorable portraits of Americans both celebrated and unfamiliar in this richly peopled book.

In 2012, an Oregon mother named Julie Keith opened up a package of Halloween decorations. The cheap foam headstones had been five dollars at Kmart. But when she opened the box, something shocking fell out: an SOS letter, handwritten in broken English. "Sir: If you occassionally buy this product, please kindly resend this letter to the World Human Right Organization. Thousands people here who are under the persicuton of the Chinese Communist Party Government will thank and remember you forever." The note's author, Sun Yi, was a mild-mannered Chinese engineer turned political prisoner, forced into grueling labor for campaigning for the freedom to join a forbidden meditation movement. He was imprisoned alongside petty criminals, civil rights activists, and tens of thousands of others the Chinese government had decided to "reeducate," carving foam gravestones and stitching clothing for more than fifteen hours a day. In Made in China, investigative journalist Amelia Pang pulls back the curtain on Sun's story and the stories of others like him, including the persecuted Uyghur minority group whose abuse and exploitation is rapidly gathering steam. What she reveals is a closely guarded network of laogai--forced labor camps--that power the rapid pace of American consumerism. Through extensive interviews and firsthand reportage, Pang shows us the true cost of America's cheap goods and shares what is ultimately a call to action--urging us to ask more questions and demand more answers from the companies we patronize.

The cold-case murder of John Hughes, the son of a Chicago Outfit member suspected of pulling the trigger, and the efforts of a determined detective to unravel a cover-up The grandson and great-grandson of Chicago police officers, Chicago Police Detective James Sherlock was CPD through-and-through. His career had seen its share of twists and turns, from his time working undercover to thwart robberies on Chicago's L trains to his years as a homicide detective. He thought he had seen it all. But on this day, he was at the records center to see the case file for the murder of John Hughes, who was seventeen years old when he was gunned down on Chicago's Southwest Side in 1976. The case's threads led everywhere: Police corruption. Hints of the Chicago Outfit. A crooked judge. Even the belief that the cover-up extended to "hizzoner" himself--legendary Chicago mayor Richard J. Daley. A murder that had roiled the city and had been investigated for years had been reduced to a few reports and photographs. What should have been a massive file with notes and transcripts from dozens of interviews was nowhere to be found. Sherlock could have left the records center without the folder and cruised into retirement, and no one would have noticed. Instead, he tucked the envelope under his arm and carried it outside.

At a time when healthcare and medical insurance are more important than ever comes this authoritative, unbiased new volume in the acclaimed Get What's Yours series. Healthcare expert Philip Moeller has written a reliable, concise guide to healthcare and health insurance basics. He provides tools that patients need before, during, and after they get medical care. He describes the care we need, the care we don't, and how to deal with doctors, hospitals, and other healthcare providers. Moeller explains telemedicine and healthcare apps that have become so important during the coronavirus epidemic. The book shares the stories of disruptive health innovators who have given us access to true health costs, cheaper prescription drugs, and low-cost care in and outside the US. You will learn how to avoid poor care, fight back against denied insurance claims and inflated bills, and use social media to connect with powerful advocates. Throughout, Get What's Yours for Healthcare draws on stories of people who share their lessons on how to successfully navigate the healthcare system.

The renowned biologist Paul Nurse has spent his career revealing how living cells work. In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every reader can understand.It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology--the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information. He introduces the scientists who made the most important advances, and, using his personal experiences in and out of the lab, he shares with us the challenges, the lucky breaks, and the thrilling eureka moments of discovery.Nurse writes with delight at life's richness and with a sense of the urgent role of biology in our time. To survive the challenges that face us all today--climate change, pandemic, loss of biodiversity and food security--it is vital that we all understand what life is.

Discover the heartwarming true story of a life-changing friendship between a man and his rescue cat, Nala, as they adventure together on a bike journey around the world -- from the Instagram phenomenon @1bike1world. When 30-year-old Dean Nicholson set off from Scotland to cycle around the world, his aim was to learn as much as he could about our troubled planet. But he hadn't bargained on the lessons he'd learn from his unlikely companion. Three months after leaving home, on a remote road in the mountains between Montenegro and Bosnia, he came across an abandoned kitten. Something about the piercing eyes and plaintive meowing of the bedraggled little cat proved irresistible. He couldn't leave her to her fate, so he put her on his bike and then, with the help of local vets, nursed her back to health. Soon on his travels with the cat he named Nala, they forged an unbreakable bond -- both curious, independent, resilient and adventurous. The video of how they met has had 20 million views and their Instagram has grown to almost 750k followers -- and still counting! Experiencing the kindness of strangers, visiting refugee camps, rescuing animals through Europe and Asia, Dean and Nala have already learned that the unexpected can be pretty amazing. Together with Garry Jenkins, writer with James Bowen of the bestselling A Street Cat Named Bob, Dean shares the extraordinary tale of his and Nala's inspiring and heart-warming adventure together.

WINNER OF FRANCE'S THE LAGARDERE PRIZE.

SHORTLISTED FOR THE INTERNATIONAL PRIZE OF ARABIC FICTION.

In her award-winning novel, Inaam Kachachi portrays the dual tragedy of her native land: America's failure and the humiliation of Iraq. The American Granddaughter depicts the American occupation of Iraq through the eyes of a young Iraqi-American woman, who returns to her country as an interpreter for the US Army. Through the narrator's conflicting emotions, we see the tragedy of a country which, having battled to emerge from dictatorship, then finds itself under foreign occupation. At the beginning of America's occupation of Iraq, Zeina returns to her war-torn homeland as an interpreter for the US Army. Her formidable grandmother--the only family member that Zeina believes she has in Iraq--gravely disapproves of her granddaughter's actions. Then Zeina meets Haider and Muhaymin, two "brothers" she knows nothing of, and falls deeply in love with Muhaymin, a militant in the Al Mehdi Army. These experiences force her to question all her values.

Celebrating the 20th anniversary of the Caine Prize for African Writing--often referred to as the African Booker Prize--this collection showcases the winning short stories of African writers from the past 20 years and reflects the vast range of modern African experience. The writers include: Leila Aboulela (2000), Helon Habila (2001), Binyavanga Wainaina (2002), Yvonne Adhiambo Owuor (2003), Brian Chikwava (2004), Segun Afolabi (2005), Mary Watson (2006), Monica Arac de Nyeko (2007), Henrietta Rose-Innes (2008), EC Osondu (2009), Olufemi Terry (2010) NoViolet Bulawayo (2011), Rotimi Babatunde (2012), Tope Folarin (2013), Okwiri Oduor (2014), Namwali Serpell (2015), Lidudumalingani (2016) Bashra al-Fadil (2017), Makena Onjerika (2018).

WINNER OF THE NOBEL PRIZE IN LITERATURE.

In a remote Polish village, Janina devotes the dark winter days to studying astrology, translating the poetry of William Blake, and taking care of the summer homes of wealthy Warsaw residents. Her reputation as a crank and a recluse is amplified by her not-so-secret preference for the company of animals over humans. Then a neighbor, Big Foot, turns up dead. Soon other bodies are discovered, in increasingly strange circumstances. As suspicions mount, Janina inserts herself into the investigation, certain that she knows whodunit, if only anyone would pay her mind. Drive Your Plow over the Bones of the Dead is a provocative exploration of the murky borderland between sanity and madness, justice and tradition, autonomy and fate. Whom do we deem sane? it asks. Who is worthy of a voice?

An electrifying work of literary suspense from internationally bestselling author Katrine Engberg, The Tenant follows two Copenhagen police detectives struggling to solve a shocking murder and stop a killer hell-bent on revenge. When a young woman is discovered brutally murdered in her own apartment with an intricate pattern of lines carved into her face, Copenhagen police detectives Jeppe Korner and Anette Werner are assigned to the case. In short order, they establish a link between the victim, Julie Stender, and her landlady, Esther de Laurenti, who's a bit too fond of drink and the host of raucous dinner parties with her artist friends. Esther also turns out to be a budding novelist--and when Julie turns up as a murder victim in the still-unfinished mystery she's writing, the link between fiction and real life grows both more urgent and more dangerous. Anette and Jeppe must dig more deeply into the two women's pasts to discover the identity of the brutal puppet-master pulling the strings.

WINNER OF THE WORLD FANTASY AWARD FOR LIFETIME ACHIEVEMENT.

Acclaimed as one of the most original voices in modern literature, Raphael Aloysius Lafferty (1914-2002) was an American original, a teller of acute, indescribably loopy tall tales whose work has been compared to that of Avram Davidson, Flannery O'Connor, Flann O'Brien, and Gene Wolfe. The Best of R. A. Lafferty presents 22 of his best flights of offbeat imagination, ranging from classics like "Nine Hundred Grandmothers" and "The Primary Education of the Cameroi" to his Hugo Award-winning "Eurema's Dam."